Advanced Cell Culture Specialist

Employer
Ellison Institute of Technology
Location
Los Angeles, California
Posted
Mar 15, 2024
Closes
Apr 12, 2024
Ref
2734330568
Discipline
Other
Position Type
Specialist
Specialty
Alternative Fuels
Hours
Full Time
Organization Type
Corporate, Other Corporate
Our Mission
Founded by Larry Ellison and David B. Agus, MD, the Ellison Institute of Technology (EIT) works to develop and deploy advanced technology in pursuit of solving some of humanity's most challenging and enduring problems. Guided by world leaders, scientists, and entrepreneurs, EIT seeks to accelerate innovation by driving scientific and technological advancements across four humane endeavors: medical sciences and health care, food security and sustainable agriculture, clean energy and climate change, and government policy and economics. Please visit for more details.

Job Summary
The Ellison Institute of Technology is seeking a talented and passionate Advanced Cell Culture Specialist to join its Cell Line Team (CLT). The CLT plays a critical role in supporting the institute with cell culture training and optimization, 2D and 3D cell culture models and relevant characterizations. At EIT, the CLT is often at the forefront of the development of new cells lines from primary tissue and new cell-based assays. The CLT, due to their high expertise, often helps execute research project assays and are involved in the subsequent data analysis. These research projects span broad focus areas that include tumor microenvironment, biophysics, and multi-scale imaging. The successful candidate will play a crucial role in establishing a biorepository of patient-derived samples including native tissues, maintaining ongoing cell cultures, and executing research project assays with data analysis, and assisting the CLT manager in supervising day to day activities of the team.

The candidate will use their cell culture expertise and research background to independently design, implement, and optimize cell culture protocols and procedures in 2D and 3D cell culture models. The ideal candidate is collaborative with experience in managing and mentoring a dynamic team.

Job Accountabilities:
  • Manage day-to-day activities of the Cell Line Team (feeding, seeding, culturing cells).
  • Assist CLT manager to supervise the team, including identifying and delegating project tasks.
  • Participate in expanding our biorepository: process fresh tissue samples for 3D organoid generation and characterization, as well as isolating autologous cancer-associated fibroblasts (CAFs).
  • Develop and optimize methods needed to expand and characterize the cell line biobank.
  • Utilize a Library Management Information System to track inventory, and an Electronic Lab Notebook to document tasks and experiments.
  • Research, compile, and evaluate background information to enhance planning and design of experiments and stay current in field of research.
  • Establish and maintain standard operating procedures (SOPs) for 2D and 3D cell culture workflows, including tissue processing, characterization, cell isolation, and maintenance.
  • Independently perform non-routine and complex research laboratory procedures and techniques.
  • Execute assays utilizing cell cultures with data analysis to support diverse research projects.
  • Present results to internal and external research teams.
  • Work collaboratively with clinical research, microscopy, and data analytics teams in support of cross-functional institute alignment.


ADDITIONAL INFORMATION

Minimum Education: Bachelor's degree in Biology or a related field

Minimum Experience: 3-5 years of work experience with tissue culture, including advanced 3D cultures. 3 years of experience with molecular biology techniques and in vitro assays, including DNA/RNA extraction, qPCR, immunofluorescence, and Western blotting. A track record of participating in peer-reviewed publications.

Minimum Field of Expertise: Cell and molecular biology; in vitro assays

Preferred Education: Master of Science in Biology or related field

Preferred Experience: 5-6 yearsof experience with tissue culture, including advanced 3D cultures. 4 years of experience with molecular biology techniques and in vitro assays, including DNA/RNA extraction, qPCR, immunofluorescence, and Western blotting.

Preferred Field of Expertise: Immunology; pharmacology; translational research

Salary: $80,000-$95,000 DOE

For the safety and health of employees, guests, and patients, the Ellison Institute of Technology may mandate vaccination requirements for employment. The Ellison Institute of Technology's policies are always subject to review and change to ensure they are appropriate under the circumstances.

The Ellison Institute of Technology is an equal opportunity employer. We believe that an inclusive, collaborative team environment is just as important to our mission as stethoscopes and microscopes. We strive to always provide employees with a supportive atmosphere, so they feel confident taking creative risks toward innovation. The Ellison Institute of Technology values emotional intelligence and communication with empathy and respect for others. We seek to build a diverse group of people who are curious, have a deep sense of responsibility, and the grit needed to achieve excellence.

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